Table 1.
Function | Tags | S, 27.7% | G2, 15.8% | M, 52.9% | G1, 3.6% |
---|---|---|---|---|---|
Cell cycle control | 30 | 5/8 (0.078) | 8/5 (0.068) | 14/16 (0.114) | 3/1 |
Cell wall | 35 | 6/10 (0.047) | 4/6 (0.136) | 25/18 (7.1e−3) | 0/1 |
Cytoskeleton | 43 | 1/12 (1.2e−5) | 4/7 (0.090) | 38/22 (2.1e−7) | 0/2 |
Hormone response | 13 | 6/4 (0.113) | 1/2 (0.277) | 6/7 (0.185) | 0/0 |
Kinases/phosphatases | 27 | 4/8 (0.039) | 1/4 (0.059) | 19/14 (0.025) | 1/1 |
Protein synthesis | 50 | 15/14 (0.116) | 5/8 (0.087) | 29/26 (0.079) | 1/2 |
Proteolysis | 21 | 2/6 (0.026) | 1/3 (0.144) | 17/11 (0.039) | 1/1 |
Replication and modification | 74 | 57/20 (4.2e−19) | 8/12 (1.0e−5) | 8/39 (1.0e−18) | 1/3 |
RNA processing | 20 | 1/6 (6.8e−3) | 1/3 (0.137) | 18/11 (8.1e−4) | 0/0 |
Signal transduction | 10 | 1/3 (0.121) | 3/2 (0.201) | 6/5 (0.205) | 2/0 |
Stress response | 20 | 6/6 (0.192) | 2/3 (0.229) | 10/10 (0.159) | 2/1 |
Transcription factors | 27 | 4/8 (0.039) | 10/4 (3.0e−3) | 12/14 (0.112) | 1/1 |
Transport and secretion | 31 | 5/9 (0.047) | 2/5 (0.076) | 21/16 (0.031) | 3/1 |
Unknown function | 175 | 37/48 (0.015) | 19/28 (0.014) | 112/93 (8.3e−4) | 7/6 |
The observed/expected number of tags within the different cell cycle phases is given together with the probability values between parentheses as calculated based on the binomial distribution function, except for the G1 phase because the figures were too small. A significant enrichment of tags of a functional group within a particular cell cycle phase is indicated in bold.
Only kinases and phosphatases with unknown biological function.
Except small GTP-binding proteins, which are classified under signal transduction.