Table 2.
Tumor incidence of Mbd4−/−/Apc1638N/+ mice
Genotype (n)
|
Age, wk
|
Sex (M:F)
|
No. (%) of mice with tumors
|
GI tract | ||
---|---|---|---|---|---|---|
Stomach (%) | Small intestine (%) | Large intestine (%) | ||||
WT/Apc1638N/+ (8) | 39.7 ± 3.0 | 1:1.7 | 7 (88) | 3 (38) | 7 (88) | 0 (0) |
Mbd4−/−/Apc1638N/+ (10) | 40.4 ± 2.5 | 1:1 | 10 (100) | 8 (80) | 10 (100) | 0 (0) |
Mean ± SD. n, Number of mice studied.