Table 1.

Percentage of T cell–DC conjugates with clustering or expulsion of MHC/peptide complexes

T cells	DCs transduced with:	AbEp	AbPCCVA	AbEp and AbPCCVA
	Exogenously added peptide:	None	None	None	PCC50E (antagonist)	PCC50Q (null)
Naive
AbPCCVA clustering		—	82  ± 15%	76  ± 13%	61  ± 21%	70  ± 9.8%
			(n = 118)	(n = 88)	(n = 103)	(n = 60)
AbEp clustering		9.2  ± 4.5%	—	4.0  ± 3.8%	62  ± 12%	7.0  ± 6.2%
		(n = 116)		(n = 67)	(n = 63)	(n = 42)
AbEp expulsion		0%	—	61  ± 7.5%	11  ± 5.2%	55  ± 8.6%
		(n = 116)		(n = 67)	(n = 63)	(n = 42)
Activated
AbPCCVA clustering		—	59  ± 19%	52  ± 12%	66  ± 14%	57  ± 8.9%
			(n = 44)	(n = 75)	(n = 54)	(n = 65)
AbEp clustering		0%	—	92  ± 6.9%	89  ± 4.7%	94  ± 3.1%
		(n = 38)		(n = 39)	(n = 36)	(n = 37)
AbEp expulsion		0%	—	0%	0%	2.1  ± 3.6%
		(n = 38)		(n = 39)	(n = 36)	(n = 37)

n = number of analyzed T cell–DC conjugates.

^*Conjugates with A^bPCCVA clustering.

^†, P = 0.001;

^‡, P = 0.024;

^§, P = 0.025 (t test, 95% confidence interval of the difference, significant when P < 0.05).