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. 2002 Oct 30;99(23):15078–15083. doi: 10.1073/pnas.232574499

Fig 3.

Fig 3.

Properties of AMPA currents in TLE mRNA-injected oocytes. (A) Inhibition of AMPA (10 μM) currents by CNQX. AMPA currents in the presence of CNQX normalized to those without CNQX (Imax = −70 nA; 6/2; 2 patients). (Inset) Superimposed traces of the current evoked by AMPA (50 μM; filled bar) and then blocked by CNQX (20 μM; open bar). (B) AMPA dose/current response relationship from 8 oocytes (3 donors; 2 patients). Imax = −268 nA. (C) AMPA current/voltage relationship from 4 oocytes (2 donors; 2 patients) with AMPA at 10 μM. AMPA currents were normalized to those obtained at −130 mV (−165 nA). Vrev = −7 mV.