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. 2002 Oct 30;99(23):15078–15083. doi: 10.1073/pnas.232574499

Fig 6.

Fig 6.

Current responses in oocytes injected with mRNA extracted from either mouse TL or human TL. (A) GABA dose/current relationship in mouse TL mRNA-injected oocytes (Imax = −274 nA; 0.5 mM GABA; 6/2). (Inset) Sample current evoked by GABA (1 mM). (B) GABA dose/current relationship from TLG mRNA-injected oocytes (○) (Imax = −25 nA; 8/2; 2 patients) compared with the GABA dose/current relationship from TLE mRNA-injected oocytes (•) described in Fig. 1C. (Inset) Sample current evoked by GABA (1 mM) in one oocyte injected with human TLG mRNA. (C) Sample currents evoked by AMPA (50 μM), KAI (200 μM), or ATPA (200 μM) in one oocyte injected with the same mRNA preparation as in A. (D) Currents evoked by the same drugs as in C in another oocyte injected with the same human TLG mRNA as for B. Note the ATPA sensitivity of the oocytes in C and D.