Table 1.

Replication of R5111 recombinant in various cell lines

Virus	Cell line	Yield
R5111	Vero	11  × 107
	HEp-2	1.2  × 107
	SK-N-SH†	17  × 107
	U87†	27  × 107
	J1.1	2  × 102
	J13R	11  × 107
HSV-1(F)	J1.1	6  × 103
	J13R	4  × 103

^*The cells were exposed to 0.01 pfu of R5111 or HSV-1(F) per cell and harvested 24 h after infection. Progeny virus was titered on Vero cells.

^† Cell lines derived from human brain tumors.