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. 2002 Nov 7;99(24):15345–15350. doi: 10.1073/pnas.232551499

Fig. 3.

Fig. 3.

(A) MEC proliferation in pregnant mice compared with nonpregnant controls after 25 days of 2H2O administration. Mating and analyses are as described in the text. (Upper) Fraction of newly divided cells (f) present. (Lower) Absolute DNA synthesis (μg). (B) Dose–response curve of MEC proliferation vs. estradiol dose administered to ovariectomized rats. Estradiol was administered by s.c. miniosmotic pump, as described in the text. f, fraction of newly divided cells present after 14 days of 2H2O administration (n = 5 per group).