Table 3.

Complementation tests with targeted alleles (KO)

ENU allele	+/+	ENU/+	+/KO	ENU/KO	Total
Smad2m1Mag	14	6	8	0 (4)	32
Smad4m1Mag	14	15	6	6	41
Smad4m2Mag	22	20	19	21	82
Smad4m3Mag	14	18	19	18	69
Smad4m4Mag	14	16	17	0	47

^*Smad2 analysis was performed at E9.5 to E11.5. Smad4 analysis was performed at postnatal stages.

^† All Smad2^m1Mag/Smad2^Robm1 concepti consisted of an empty yolk sac.