. 2002 Nov 14;99(24):15590–15595. doi: 10.1073/pnas.242134499

Table 2.

Efficiency of HIV-1 R5 reverse transcription and integration in HOS^low and HOS^high cells

Cells	Late transcripts day 2, copies/10⁶ cells	Integration day 15, copies/10⁶ cells	Virus production day 15, arbitrary units of luciferase activity
HOS^low	238 ± 65	189 ± 133	3,154 ± 1,276
HOS^high	6,292 ± 1,879	4,464 ± 997	103,220 ± 24,043
HOS^high/HOS^low	26 ± 7	24 ± 5	33 ± 7

HOS^low and HOS^high cells were exposed to 500 ng of p24 of env-defective HIV-1 R5 virus harboring the luciferase marker gene and analyzed at different times. The number of late transcripts was determined by LTR-gag quantitative PCR at day 2. The number of integrated proviral DNA copies was determined by LTR-LTR quantitative PCR at day 15. Virus production was also quantitated at day 15 by measuring luciferase activity.