Table 3.
Effects of different dietary AGE consumption on metabolic variables during 2-week and 6-week studies
|
|
2-week crossover study | 6-week study | ||||||
|---|---|---|---|---|---|---|---|---|
| H-AGE | L-AGE | |||||||
| H-AGE | L-AGE | P | Baseline | 6 weeks | Baseline | 6 weeks | P | |
| Body weight, kg | 81.7 ± 4.2 | 81.2 ± 4.2 | 0.2 | 89.1 ± 7 | 88.9 ± 6.8 | 72 ± 7.2 | 70.4 ± 7.5 | 0.02 |
| Systolic blood pressure, mmHg | 126 ± 3.9 | 133 ± 4.5 | 0.2 | 125.2 ± 3.7 | 127 ± 2 | 127.1 ± 3 | 122 ± 6 | 0.3 |
| Diastolic blood pressure, mmHg | 73 ± 3 | 72 ± 2.6 | 0.6 | 60.7 ± 4 | 63 ± 2 | 67.6 ± 5 | 64 ± 5 | 0.4 |
| Fasting glucose, mmol/liter | 7.5 ± 0.7 | 8.1 ± 0.4 | 0.5 | 6.5 ± 1.2 | 8.1 ± 1.1 | 7.0 ± 1 | 5.6 ± 0.5 | 0.02 |
| Fructosamine, mmol/liter | 319 ± 11 | 325 ± 13 | 0.3 | 299.3 ± 21 | 324 ± 15 | 345 ± 20.3 | 281 ± 13 | 0.8 |
| Cholesterol, mmol/liter | 4.6 ± 0.2 | 4.5 ± 0.3 | 0.4 | 4.97 ± 0.6 | 4.6 ± 0.6 | 4.4 ± 0.2 | 4.4 ± 0.2 | 0.2 |
| LDL cholesterol, mmol/liter | 2.7 ± 0.1 | 2.6 ± 0.2 | 0.1 | 2.86 ± 0.2 | 2.7 ± 0.5 | 2.4 ± 0.1 | 2.5 ± 0.2 | 0.1 |
| HDL cholesterol, mmol/liter | 1.3 ± 0.07 | 1.2 ± 0.1 | 0.1 | 1.53 ± 0.15 | 1.4 ± 0.2 | 1.38 ± 0.1 | 1.3 ± 0.1 | 0.2 |
| Triglycerides, mmol/liter | 1.2 ± 0.1 | 1.3 ± 0.1 | 0.4 | 1.25 ± 0.1 | 1.2 ± 0.1 | 1.15 ± 0.08 | 1.1 ± 0.1 | 0.9 |
Results are expressed as means ± SEM. HDL, high density lipoprotein.
*
P values refer to the significance between last day of the H-AGE and L-AGE diets.
†
H-AGE, n = 6; L-AGE, n = 7. P values refer to significance of percentage change (from baseline to 6 weeks) of H-AGE versus L-AGE.