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. 2006 Feb 24;2(2):e8. doi: 10.1371/journal.pgen.0020008

Figure 4. Domain Organization of Prokaryotic NHEJ Repair Enzymes.

Figure 4

Prokaryotic NHEJ DNA ligases exhibit a variety of arrangements of catalytic domains. Representative examples are presented showing the approximate location of the individual domains (amino acid): from Mt, Mt-LigD (polymerase, 1–280; nuclease, 281–460; ligase, 461–760); from P. aeruginosa, PA2138 (nuclease, 1–200; ligase, 201–550; polymerase, 551–841); and from B. subtilis, YkoU (ligase, 1–320; polymerase, 321–611). Putative “stand-alone” NHEJ proteins containing related DNA ligase, polymerase, and nuclease domains are also included—SCO refers to S. coelicolor and AF refers to A. fulgidus.