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. 2002 Dec 1;30(23):5160–5167. doi: 10.1093/nar/gkf651

Table 3. Oligomer sequence, Tm values and inhibition of luciferase activity data for LNA–DNA chimeras that target the downstream coding region of luciferase mRNA.

ID Sequence 5′→3′ Tm (°C) DNA:DNA Tm (°C) LNA:DNA Inhibition (%)
        25 nM 100 nM 200 nM
XXVI GtcgTtCgCGGGCgC 61 77 23 40 55
XXVII TGtAgccATcCaTCC 47 78 0 0 0
XXVIII CGGTtccatccTCTA 55 69 60 61 78
XXIX TTGTattcagcCCAT 52 68 33 39 69
XXX GTCGttcgcggGCGC 71 81 82 94 95
XXXI GCTGttcgcggCGGC 69 78 6 7 8
XXXII TGTAgccatccATCC 47 78 29 39 53

Capitalized letters within a sequence represent LNA, lower case letters represent DNA bases and underlined bases depict mismatched bases relative to luciferase mRNA.