Figure 1.
Sequence alignment of the protein subunit of RNase P from various bacteria. Although a ClustalW-based alignment of 112 homologs from 10 different phylogenetic groups of Bacteria was performed, only 14 representative sequences (E.coli, B.subtilis, Corynebacterium diphtheriae, Caulobacter crescentus, Campylobacter jejuni, Neisseria gonorrhoeae, Synechocystis sp. PCC 6803, Treponema denticola, Chlamydophila psittaci, Thermotoga maritima, Porphyromonas gingivalis, Deinococcus radiodurans, Chlorobium tepidum and Dehalococcoides ethenogenes) are shown in this illustration. Two sets of conserved residues at positions which exhibit at least 67% identity in the complete alignment are highlighted in blue and brown. †The demarcation of secondary structure elements is based on the tertiary structure of the protein subunit of B.subtilis RNase P (22).