Scheme 1. Schematic representation of the interstrand cross-linking rearrangement of a 1,3-trans-{Pt(NH3)2[d(GXG)-N7G, N7G]} chelate (noted G*XG* in the text) within a duplex DNA (8). The half circle, crossed by a line, indicates the 1,3-N7G, N7G chelate of the trans-Pt(NH3)2 moiety.