Table 4.

Most Frequent Override Reasons Provided by Clinician

Contraindication	Override Reasons (%)
Duplicate class	Transitioning from one medication to other (42)
	Patient is on long-term therapy with combination (21)
	Short-term or as-needed dosing (7)
Drug-drug	Will monitor as recommended (49)
	Patient has already tolerated combination (21)
	Will adjust dose as recommended (14)
Drug-lab	Will monitor/manage as recommended (67)
	More recent lab result available that warrants use (18)
Drug-disease	Patient has tolerated this drug in the past (56)
	New evidence supports therapy of this type (22)
Drug-pregnancy	Patient is not pregnant (90)
	Patient is not of child-bearing potential (5)