Table 7.
Mean duration (SEM) of temporal measures of swallowing by treatment protocol 3 months after chemoradiation treatment. (PPW = posterior pharyngeal wall).
| TFHX, taxol infusion | TFHX, taxol bolus | TFHX, bolus, induction | RADPLAT | p value | |
|---|---|---|---|---|---|
| Number of swallows | 70 | 98 | 69 | 73 | |
| Oral onset of swallow (s) | −1.25 (.20) | −1.35 (.21) | −1.43 (.35) | −1.14 (.23) | .81 |
| Duration of oral transit time (s) | 0.56 (.13) | 0.70 (.13) | 0.39 (.11) | 0.18 (.15) | .02* |
| Duration of pharyngeal transit time (s) | 0.76 (.04) | 0.93 (.05) | 0.85 (.04) | 0.88 (.05) | .04* |
| Duration of pharyngeal delay (s) | −0.06 (.05) | −0.05 (.05) | 0.01 (.04) | −0.05 (.06) | .58 |
| Duration of tongue base contact to PPW at level of mid-C2 (s) | 0.41 (.07) | 0.33 (.07) | 0.48 (.06) | 0.45 (.08) | .34 |
| Duration of tongue base contact to PPW at level of inferior C2 (s) | 0.41 (.07) | 0.24 (.07) | 0.33 (.06) | 0.28 (.08) | .34 |
| Duration of tongue base contact to PPW at level of superior C3 (s) | 0.39 (.06) | 0.15 (.06) | 0.37 (.05) | 0.27 (.07) | .02* |
| Duration of velopharyngeal closure (s) | 0.82 (.09) | 0.75 (.09) | 0.74 (.08) | 0.85 (.10) | .70 |
| Duration of laryngeal closure (s) | 0.58 (.08) | 0.47 (.08) | 0.72 (.07) | 0.54 (.08) | .13 |
| Duration of cricopharyngeal opening (s) | 0.54 (.02) | 0.58 (.02) | 0.59 (.02) | 0.56 (.03) | .30 |
| Duration of laryngeal elevation (s) | 1.18 (.10) | 1.16 (.10) | 1.27 (.08) | 1.22 (.11) | .79 |
| Duration of hyoid elevation (s) | 1.22 (.10) | 1.16 (.10) | 1.26 (.09) | 1.18 (.11) | .88 |
| Onset base of tongue to posterior pharyngeal wall (s) | 0.16 (.02) | 0.18 (.01) | 0.15 (.01) | 0.18 (.02) | .50 |
| Time from first airway closure to first cricopharyngeal opening (s) | 0.04 (.05) | 0.01 (.05) | −0.02 (.05) | 0.06 (.05) | .68 |
| Oral residue (% of bolus) | 5.6 (2.0) | 9.4 (2.0) | 5.5 (1.8) | 5.04 (2.38) | .29 |
| Pharyngeal residue (% of bolus) | 13.8 (2.4) | 13.5 (2.5) | 10.6 (2.2) | 13.5 (2.8) | .67 |
| Aspiration (% of bolus aspirated) | 0.34 (.09) | 0.17 (.10) | 0.09 (.09) | 0.00 | .04* |
| Oropharyngeal swallow efficiency (%/s) | 76 (5) | 66 (5) | 74 (4) | 78 (6) | .32 |
| Number of attempts to swallow 1st bolus | 2.04 (.23) | 2.06 (.24) | 2.24 (.20) | 1.97 (.28) | .84 |
| % of patients with G-tubes | 46 | 50 | 20 | 44 | .33 |
| % of patients with oral intake ≤ 50% | 31 | 19 | 13 | 33 | .58 |
| % of patients aspirating | 54 | 19 | 13 | 0 | .02* |
Abbreviation: PPW, posterior pharyngeal wall.
*
p < .05.