Table 4.
Maximal LOD Scores for Each Chromosome Derived from the Genomewide Scan with Recessive and Dominant Disease Models[Note]
Dominant Model |
Recessive Model |
||||
Chromosomeand Position (cM) | Marker | LOD | θ | LOD | θ |
1: | |||||
179.98 | D1S1625 | .918 | 0 | 1.160 | 0 |
218.46 | D1S1678 | 1.667 | 0 | .513 | .1 |
2: | |||||
47.97 | D2S405 | .127 | .2 | .218 | .15 |
99.41 | D2S1777 | .708 | 0 | −.172 | .2 |
3: | |||||
89.91 | D3S4542 | .986 | 0 | 1.702 | 0 |
4: | |||||
33.96 | D4S3340 | −.412 | .2 | .655 | 0 |
60.16 | D4S1627 | .155 | .2 | −.515 | .2 |
5: | |||||
168.49 | D5S1475 | .840 | 0 | .887 | .1 |
6: | |||||
92.85 | D6S1270 | 1.313 | 0 | .040 | .2 |
102.81 | D6S1056 | −.063 | 0 | 1.480 | 0 |
7: | |||||
17.17 | D7S2200 | .901 | 0 | .112 | .2 |
103.63 | D7S1813 | .562 | 0 | .273 | .1 |
8: | |||||
26.43 | D8S1106 | .400 | 0 | −.484 | .2 |
94.17 | D8S1123 | −.159 | .2 | .005 | .15 |
9: | |||||
163.84 | D9S1838 | 1.834 | 0 | 3.341 | 0 |
10: | |||||
109.98 | D10S1739 | 1.322 | 0 | .538 | .075 |
117.42 | D10S677 | 1.489 | 0 | .136 | .15 |
11: | |||||
33.02 | ATA34E08 | −.141 | .2 | .409 | .2 |
123.00 | D11S4464 | .975 | 0 | .267 | .15 |
12: | |||||
56.38 | D12S1663 | 1.150 | 0 | .247 | .15 |
13: | |||||
63.90 | D13S317 | .261 | .2 | −.089 | .2 |
14: | |||||
55.82 | D14S587 | .753 | 0 | −.059 | .2 |
105.53 | D14S617 | −.092 | .2 | .724 | .025 |
15: | |||||
52.33 | D15S643 | .202 | .1 | −.003 | .2 |
60.17 | D15S1507 | −.213 | .1 | .631 | .1 |
16: | |||||
8.16 | D16S2622 | .225 | .2 | .692 | .025 |
17: | |||||
.63 | D17S1308 | −.172 | .2 | .097 | .15 |
82.00 | D17S1290 | .013 | .2 | .010 | .2 |
18: | |||||
96.48 | D18S1270 | .728 | 0 | .773 | .05 |
19: | |||||
68.08 | D19S178 | .417 | .15 | .329 | .1 |
92.56 | D19S418 | .591 | .05 | .115 | .2 |
20: | |||||
21.15 | D20S115 | .628 | 0 | −.115 | .2 |
42.28 | D20S471 | .089 | .2 | .123 | .2 |
21: | |||||
36.77 | D21S1440 | .419 | 0 | .703 | .075 |
22: | |||||
24.74 | D22S1167 | .503 | .1 | −.047 | .2 |
32.39 | D22S685 | −.155 | .2 | .173 | .2 |
X: | |||||
52.63 | DXS1068 | .379 | .075 | 1.027 | .001 |
165.11 | DXS9908 | .419 | .1 | −.120 | .2 |
Note.— See the “Methods” section for a detailed description of the search for the genetic locus of HHRH. LOD scores are not corrected for multiple testing.