Table 3.
Odds Ratios of Microbe Colonization by Nonoxynol-9 Delivery System, Adjusted for Baseline Colonization
| Microbe/Nonoxynol-9 Formulation | Odds Ratio (95% Confidence Interval) |
|---|---|
| H2O2+ Lactobacilli | |
| 52.5-mg gel | 1.0 (referent) |
| 100-mg gel | 0.8 (0.3–2.0) |
| 150-mg gel | 0.7 (0.4–1.4) |
| 100-mg film | 0.5 (0.2–1.1) |
| 100-mg suppository | 0.7 (0.3–1.5) |
| H2O2– Lactobacilli | |
| 52.5-mg gel | 1.0 (referent) |
| 100-mg gel | 0.9 (0.4–1.9) |
| 150-mg gel | 1.2 (0.5–2.9) |
| 100-mg film | 0.8 (0.4–1.7) |
| 100-mg suppository | 1.3 (0.6–2.9) |
| Gardnerella vaginalis | |
| 52.5-mg gel | 1.0 (referent) |
| 100-mg gel | 1.1 (0.5–2.6) |
| 150-mg gel | 0.8 (0.4–1.9) |
| 100-mg film | 1.4 (0.7–3.0) |
| 100-mg suppository | 1.0 (0.4–2.2) |
| Escherichia coli | |
| 52.5-mg gel | 1.0 (referent) |
| 100-mg gel | 0.7 (0.4–1.3) |
| 150-mg gel | 1.0 (0.6–1.8) |
| 100-mg film | 0.7 (0.4–1.4) |
| 100-mg suppository | 1.4 (0.8–2.6) |
| Enterococcus | |
| 52.5-mg gel | 1.0 (referent) |
| 100-mg gel | 0.5 (0.2–0.9) |
| 150-mg gel | 0.6 (0.3–1.2) |
| 100-mg film | 0.5 (0.3–1.0) |
| 100-mg suppository | 0.9 (0.4–1.9) |
| Anaerobic gram-negative rods | |
| 52.5-mg gel | 1.0 (referent) |
| 100-mg gel | 3.6 (1.3–10.4) |
| 150-mg gel | 1.7 (0.7–4.0) |
| 100-mg film | 1.0 (0.5–2.3) |
| 100-mg suppository | 2.3(0.9–5.6) |
| Bacterial Vaginosis gram stain | |
| 52.5-mg gel | 1.0 (referent) |
| 100-mg gel | 2.0 (0.8–5.4) |
| 150-mg gel | 1.2 (0.5–2.4) |
| 100-mg film | 1.4 (0.6–3.5) |
| 100-mg suppository | 0.7 (0.4–1.4) |
| Yeast | |
| 52.5-mg gel | 1.0 (referent) |
| 100-mg gel | 0.9 (0.4–2.4) |
| 150-mg gel | 0.4 (0.1–1.1) |
| 100-mg film | 0.1 (0.02–0.5) |
| 100-mg suppository | 0.4 (0.1–0.96) |