EhLRRP1 is found among surface labeled proteins of E. histolytica. Immunoblotting of total lysate (T) or a biotin-labeled surface protein fraction (S) from E. histolytica trophozoites with either a monoclonal antibody to actin, a monoclonal antibody to SREHP, or polyclonal antiserum to EhLRRP1. Bands at the appropriate molecular weight (41 kDa for actin, approximately 50 kDa for SREHP, and 100 kDa for EhLRRP1) were detected in both fractions for SREHP and EhLRRP1, but only the total lysate for actin.