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Amino acid alignment of the p53 proline-rich domain from different primates. Schematic representation of p53 protein (AD: activator domain, PR: proline-rich domain; DB: DNA-binding domain; TD: tetramerization domain; and RD: C-terminal regulatory domain). The proline-rich domain containing Arg72 (arrowhead) was sequenced in different primate species and aligned to the human sequence.
