Table 1.
Immunohistochemical markers in the differential diagnosis of MCC.
| CK-20 | TTF-1 | NSE | S-100 | GrA | SYP | NFP | CD56 | MAP-2 | LCA | |
| MCC | + | - | + | - | +/- | +/- | + | + | + | - |
| SCLC | - | + | +/- | - | -/+ | + | -/+ | + | + | - |
| MM | - | - | - | + | - | - | + | - | ||
| LGNEC | + | + | + | + | -/+ | |||||
| Malignant lymphoma | - | - | - | - | - | -/+ | + |
+ positive, +/- mostly positive, -/+ mostly negative, - negative. CK-20 cytokeratin 20, TTF-1 thyroid transcription factor 1, NSE neuron-spesific enolase, GrA gromogranin A, NFP neurofilament proteins, CD56 neural adhesion molecule, MAP-2 microtubule associated protein 2, LCA leukocyte common antigen SCLC small cell lung carcinoma, MM malignant melanoma, LGNEC low grade neuroendocrine carcinomas