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. 2006 Mar;17(3):1250–1260. doi: 10.1091/mbc.E05-08-0794

Figure 1.

Figure 1.

KEL-8 regulates GLR-1 abundance in dendrites. GLR-1::GFP (A and B), SNB-1::GFP (C and D), UNC-43::GFP (E and F), and LIN-10::GFP (G and H) fluorescence was observed along the ventral cord dendrites of wild-type nematodes (A, C, E, and G) or kel-8 mutants (B, D, F, and H). Whereas wild-type animals have small clusters of GLR-1::GFP (100%; n = 20), most kel-8 mutants have large (>2-μm) clusters of GLR-1::GFP (95%; n = 20). Bar, 5 μm. The mean cluster area (I) and the mean number of clusters per 10 μm (J) of ventral cord length is plotted for adult nematodes of the given genotype and expressing the transgene indicated beneath the graph. White bars indicate wild-type animals, whereas black bars indicate kel-8 mutants. AU, arbitrary units. Error bars are SEM for all graphs. ***p < 0.0001 and **p < 0.001 compared with wild type expressing the corresponding transgene by Student's t test. n = 15–20 animals for each genotype–transgene combination.