Table 2.
Genes with the highest increase in PAF upon stress
| Wild type
|
rck2Δ
|
rck2-kd
|
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| ORF | Gene | Description | Fold PAF increase | ORF | Gene | Description | Fold PAF increase | ORF | Gene | Description | Fold PAF increase |
| YPL162C | 7.2 | YIL052C | RPL34B | Ribosome (cytosolic) | 10.8 | YNR040W | 6.2 | ||||
| YDL229W | SSB1 | Heat-shock protein | 5.5 | YGL147C | RPL9A | Ribosome (cytosolic) | 8.0 | YLR343W | 5.8 | ||
| YCL042W | 4.9 | YLR325C | RPL38 | Ribosome (cytosolic) | 7.6 | YCL042W | 5.1 | ||||
| YMR011W | HXT2 | Hexose transporter | 3.7 | YDL191W | RPL35A | Ribosome (cytosolic) | 7.6 | YHR081W | LRP1 | rRNA processing | 4.8 |
| YDR101C | ARX1 | Ribosomal biogenesis | 3.6 | YBL027W | RPL19A | Ribosome (cytosolic) | 7.5 | YOR181W | LAS17 | Actin assembly | 4.3 |
| YDR411C | 3.5 | YOR096W | RPS7A | Ribosome (cytosolic) | 7.5 | YKR002W | PAP1 | Polyadenylation | 4.2 | ||
| YAL040C | CLN3 | Cyclin | 3.5 | YER056C-A | RPL34A | Ribosome (cytosolic) | 7.2 | YNL009W | IDP3 | Isocitrate dehydrogenase | 4.0 |
| YOR161C | PNS1 | 3.4 | YLR062C | Overlaps with RPL22A | 6.9 | YMR011W | HXT2 | Hexose transporter | 4.0 | ||
| YDL213C | NOP6 | rRNA processing | 3.3 | YNL174W | 6.4 | YKL009W | MRT4 | rRNA processing | 3.9 | ||
| YDR133C | 3.2 | YKL009W | MRT4 | rRNA processing | 6.4 | YGR103W | NOP7 | rRNA processing | 3.8 | ||
| YER091C | MET6 | Methionine biosynthesis | 3.2 | YJL177W | RPL17B | Ribosome (cytosolic) | 6.3 | YLR198C | 3.7 | ||
| YLR269C | 3.0 | YKL180W | RPL17A | Ribosome (cytosolic) | 6.3 | YDL222C | FMP45 | 3.7 | |||
| GL209W | MIG2 | Transcription factor | 2.9 | YDL208W | NHP2 | rRNA processing | 6.1 | YML093W | UTP14 | rRNA processing | 3.6 |
| YDL222C | FMP45 | Cell wall | 2.9 | YKL156W | RPS27A | Ribosome (cytosolic) | 5.9 | YLR302C | 3.4 | ||
| YLL061W | MMP1 | Amino acid permease | 2.8 | YDR449C | UTP6 | rRNA processing | 5.8 | YOL077C | BRX1 | rRNA processing | 3.4 |
| YKL043W | PHD1 | Transcription factor | 2.7 | YPL079W | RPL21B | Ribosome (cytosolic) | 5.7 | YLR042C | 3.4 | ||
| YKL060C | FBA1 | Glycolysis, gluconeogenesis | 2.7 | YJL188C | Overlaps with RPL39 | 5.6 | YLR197W | SIK1 | rRNA processing | 3.4 | |
| YDR476C | 2.7 | YKL172W | EBP2 | rRNA processing | 5.5 | YKR081C | RPF2 | rRNA processing | 3.3 | ||
| YGL215W | CLG1 | Cyclin-like | 2.7 | YPL090C | RPS6A | Ribosome (cytosolic) | 5.5 | YGL209W | MIG2 | Transcription factor | 3.3 |
| YGR162W | TIF4631 | eIF-4γ | 2.6 | YDR184C | BAT1 | Nuclear | 5.4 | YOR004W | rRNA processing | 3.2 | |
| YCL040W | GLK1 | Glucokinase | 2.6 | YHR049W | FSH1 | rRNA processing | 5.3 | YDR365C | ESF1 | rRNA processing | 3.2 |
| YDR324C | UTP4 | rRNA processing | 2.6 | YOR310C | NOP58 | rRNA processing | 5.3 | YHR196W | UTP9 | rRNA processing | 3.2 |
| YJR027W | Ty element | 2.6 | YHR152W | SPO12 | nucleolar | 5.2 | YKL097C | 3.2 | |||
| YLR197W | SIK1 | rRNA processing | 2.6 | YHR099W | TRA1 | HAT complex | 5.1 | YMR321C | 3.1 | ||
| YBR092C | PHO3 | Phosphatase | 2.6 | YGR085C | RPL11B | Ribosome (cytosolic) | 5.1 | YDR324C | UTP4 | rRNA processing | 3.1 |
| YDR483W | KRE2 | Protein glycosylation | 2.6 | YLR197W | SIK1 | rRNA processing | 5.1 | YJL163C | 3.1 | ||
| YDR072C | IPT1 | Sphingolipid metabolism | 2.6 | YLR293C | GSP1 | rRNA processing | 4.9 | YNL175C | NOP13 | rRNA processing? | 3.1 |
| YDL134C | PPH21 | Protein phosphatase | 2.6 | YJL189W | RPL39 | Ribosome (cytosolic) | 4.8 | YGR192C | TDH3 | Glycolysis, gluconeogenesis | 3.1 |
| YNL110C | NOP15 | Ribosome biogenesis | 2.6 | YGR148C | RPL24B | Ribosome (cytosolic) | 4.7 | YDR184C | BAT1 | 3.0 | |
| YIL074C | SER33 | Serine biosynthesis | 2.5 | YGL078C | DBP3 | rRNA processing | 4.7 | YKL043W | PHD1 | 3.0 | |
Genes for proteins involved in ribosomal biogenesis and rRNA processing are bold; cytosolic ribosomal proteins are italicized.