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Phylogenetic tree of CLCA family members, including the first equine homolog, eCLCA1. The eCLCA1 polypeptide sequence is part of a cluster (gray box) also containing its direct orthologs, the human hCLCA1, the murine mCLCA3 (alias gob-5), and the porcine pCLCA1. The scale bar represents 5% polypeptide sequence diversity. The tree was constructed using a Clustal W alignment in the DNAStar sequence analysis software.
