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. 2006 Jan 26;25(3):447–456. doi: 10.1038/sj.emboj.7600947

Figure 2.

Figure 2

Structure of the putative CCR5-binding region of RANTES. Molecular surface representation (by GRASP) of the NMR solution structure of the RANTES dimer showing a large hydrophobic surface, lined by charged residues, where critical amino acids for CCR5 interaction and anti-HIV activity were mapped. Blue denotes positive electrical charge; red, negative charge; white, no charge (adapted from Nardese et al, 2001).