Skip to main content
. 2006 Feb 24;394(Pt 3):581–592. doi: 10.1042/BJ20051471

Figure 8. Selective inhibition of PI3K-C2α protein expression by siRNA specific to PI3K-C2α.

Figure 8

(A) Effects of C2α-siRNA (PI3K-C2α-specific siRNA) on protein expression. (B) Effects of p110α-siRNA (p110α-specific siRNA) on protein expression. In (A) and (B), the VSMCs were transfected with C2α-siRNA, p110α-siRNA or sc-siRNA with or without the EGFP expression vector pEGFP, and were analysed for PI3K-C2α, p110α, smooth muscle α-actin (αSMA) and MLCK protein expression by Western blotting. (C) and (D) Quantitative data of the expression of PI3K-C2α and p110α proteins. *, P<0.01 compared with sc-siRNA-treated control.