Figure 5. Summary of the calpain-2 and caspase-3 degradomes and differential TBI proteome results from HTPI.

(A) The number of putative degradomic hits for each template based on calpain-2 versus naïve, caspase-3 versus naïve, and TBI versus naïve comparisons were tabulated. The total number of degradome hits is listed on the far right. (B) Venn diagram showing overlap of protein targets in the 3 degradomes (calpain, dashed line; caspase-3, dotted line; TBI, solid line). The total number of protein targets is in brackets. Overlaps and triple overlap numbers are indicated.