Table 2.
Statistical Analysis of 10-mer-Initiation Region Consensus
| Subset | % Total ARE mRNAa | No. total consensus sitesb | Initiation sites (% of consensus sites)cd | No. ARE mRNA (% total)fe |
|---|---|---|---|---|
| Aa | 5 | 346 | 29 (8%) | 210 (35%) |
| Ca | 9 | 175 | 53 (30%) | 147 (25%) |
| Ga | 5.3 | 142 | 31 (22%) | 126 (21%) |
| Ta | 4.1 | 59 | 24 (41%) | 57 (9%) |
| Ac | 2.2 | 214 | 13 (6%) | 148 (25%) |
| Cc | 5.5 | 67 | 32 (48%) | 65 (11) |
| Gc | 6.4 | 53 | 37 (71%) | 52 (9%) |
| Tc | 2.2 | 98 | 13 (13%) | 80 (13%) |
| Ag | 9.7 | 243 | 56 (23%) | 172 (29%) |
| Cg | 22.4 | 225 | 130 (58%) | 170 (28%) |
| Gg | 10.4 | 217 | 60 (28%) | 175 (29%) |
| Tg | 3.8 | 91 | 22 (24%) | 59 (10%) |
| At | 3.4 | 64 | 20 (31%) | 66 (11%) |
| Ct | 5.5 | 153 | 32 (21%) | 134 (22%) |
| Gt | 3.3 | 177 | 19 (11%) | 128 (21%) |
| Tt | 1.4 | 43 | 8 (19%) | 43 (7%) |
Consensuses, based on the 16 divisions from Table 1, were statistically analyzed in relation to the overall 605 ARE mRNA entries. Each subset contains the ARE mRNAs in which consensuses were derived from their initiation regions; their percentages were given. The 10-mer consensus of each subset was used in the FindPattern program to search matching patterns in the overall 605 ARE mRNA database.
Total number of matching sites including both initiation and internal sites in ARE mRNA sequences.
Number of consensus sites unique to the initiation regions that also equals the ARE mRNAs in each subset.
Percentages of consensuses in the initiation sites compared with all sites (initiation and internal sites) at each subset.
Number of sequences of fpercentages of the overall 605 ARE mRNA sequences that contained the consensus pattern (both initiation and internal).