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. 2002 Jun;12(6):868–884. doi: 10.1101/gr.229002

Figure 5.

Figure 5

Putative regulatory elements shared between groups of correlated and anticorrelated genes. There were three groups of correlated (+) genes: (1) SIAT9, HIVEP2, SEPP1, SCYD1, NEFL, INA; (2) CUGBP2, MBP, CBLN1; (3) CBLN1, USP9X, PNUTL2; and one group of anticorrelated (−) genes: (1) MBP, NEFL, CBLN1, PNUTL2, USP9X. The groups are indicated by square brackets. Genes are indicated by UniGene symbol or name (http://www.ncbi.nlm.nih.gov/UniGene). Exons are indicated by short vertical lines and the direction of transcription by horizontal arrows. Homology searches were performed on human homologs of the relevant mouse genes. In all cases, the human gene has the same symbol as the mouse, except for ahuman NEFL = mouse Nfl, and bhuman PNUTL2 = mouse Sept4. The regulatory sequences responsible for correlated expression are shown as squares, those responsible for anticorrelated expression are shown as diamonds. Lines delineate the relationships between the conserved regulatory sequences. Multiple control regions frequently connected the genes. Potential binding sites are: (1) LMO2COM, (2) OCT1, (3) GATA2 and GATA3, (4) MYOD, (5) LMO2COM, (6) NFAT, (7) GFI1, (8) TCF11, (9) HFH2, (10) GFI1, (11) NFAT, (12) FREAC2, (13) OCT1, (14,15) GKLF, (16) TATA, (17) SRY, (18) TH1E47, (19) SRY, (20) HFH2, (21) BARBIE, (22) HFH2, (23) HFH3, (24) HNF3B, (25) HFH2, (26,27) HFH8 and HFH3, (28) HFH-3, (29) GATA, (30) CEBPB, (31) MYOD, (32) LMO2COM, (33) E47, (34) SRY, (35) NFAT, (36) CETS1P54. (*) No known transcription factor binding site.