Table 1.
Patient Characteristics by Fasting Plasma Glucose Stage
| Normal Glucose (< 100mg/dL) |
Stage 1 IFG (100-109mg/dL) |
Stage 2 IFG (110-125mg/dL) |
|
|---|---|---|---|
| Number of Subjects | 28,335 | 18,738 | 12,878 |
| Age in Years1,2 | 58.6 (11.6) | 58.3 (11.5) | 59.5 (11.5) |
| Percent Female | 54.0% | 53.7% | 54.7% |
| Months of Observation1 | 59.3 (37.9) | 59.8 (36.2) | 50.7 (36.0) |
| History of Smoking1,3 | 18.8% | 21.7% | 22.1% |
| Comorbidities: | |||
| History of MI1,2,3 | 5.1% | 7.1% | 7.9% |
| History of Stroke1,2 | 7.5% | 8.1% | 9.1% |
| ASCVD1,2,3 | 12.1% | 17.3% | 19.8% |
| CHF1,2,3 | 5.6% | 7.0% | 9.2% |
| Depression1,3 | 19.1% | 21.0% | 21.0% |
| Died in Stage2,3 | 7.2% | 6.0% | 7.7% |
| Pharmaceutical Utilization: | |||
| Anti-Hypertensive Agents1,2,3 | 52.4% | 66.5% | 70.4% |
| Lipid Lowering Agents1,2,3 | 24.8% | 38.2% | 40.7% |
| Other CVD Medications1,3 | 28.6% | 34.6% | 35.3% |
| Anti-Depressants2,3 | 31.9% | 34.8% | 32.8% |
| Systolic Blood Pressure (mmHg)1,2,3 | 131 (14) | 135 (13) | 137 (13) |
| Diastolic Blood Pressure (mmHg)1,3 | 79 (7) | 80 (7) | 80 (8) |
| LDL Cholesterol (mg/dl)1,2 | 130 (32) | 130 (32) | 125 (31) |
| HDL Cholesterol (mg/dl)1,2,3 | 52 (16) | 49 (14) | 47 (13) |
| Triglycerides (mg/dl)1,2,3 | 156 (103) | 189 (156) | 208 (163) |
| Total Cholesterol (mg/dl)2,3 | 212 (36) | 215 (39) | 211 (39) |
| Body Mass Index (kg/m2)1,2,3 | 28.6 (5.4) | 31.3 (6.4) | 32.7 (6.9) |
| Number of Metabolic Syndrome Criteria (triglycerides, HDL, BP)1,2,3 | |||
| None | 23.7% | 12.8% | 8.1% |
| One | 38.7% | 34.3% | 29.6% |
| Two | 26.2% | 32.8% | 35.1% |
| All three | 11.5% | 20.2% | 27.2% |
| Annual Clinic Visits1,2,3 | 9.3 (11.3) | 9.7 (8.8) | 11.4 (17.2) |
| Annual Pharmaceutical Dispenses1,2,3 | 16.6 (19.2) | 19.8 (21.8) | 22.8 (46.3) |
1
Normal glucose group differs from Stage 2, p<.001
2
Stage 1 differs from Stage 2, p<.001
3
Normal glucose group differs from Stage 1, p<.001
Note: Numbers shown are means (standard deviations) or proportions (%).