Table 3. Kinetic parameters for the wild-type LdAdK with Ado analogues.
Wild-type LdAdK | ||||
---|---|---|---|---|
Substrate | Km (μM) | kcat (min−1) | kcat/Km (μM−1. min−1) | Ki (Ado) (mM) |
Ado | 5.5±1.5 | 1449±130 | 263.4 | − |
2′-Deoxyadenosine | 77±5 | 315±8 | 4.09 | 15.75 |
3′-Deoxyadenosine | 36±3 | 403±15 | 11.19 | 3.3 |