Skip to main content
. 2006 Jan 27;394(Pt 1):105–114. doi: 10.1042/BJ20051574

Table 2. Antibacterial and antifungal activities of HP (2-20) and its analogues.

MIC [μM]
ME* HP A1 A2 A3 A4 A5 A6 A7
Bacteria
B. subtilis 0.78 3.13 1.56 1.56 1.56 6.25 3.13 1.56 1.56
S. epidermidis 3.13 6.25 3.13 3.13 3.13 >12.5 12.5 6.25 3.13
S. aureus 0.78 12.5 3.13 6.25 1.56 >12.5 >12.5 3.13 3.13
E. coli 0.78 3.13 0.78 3.13 1.56 12.5 6.25 3.13 3.13
S. typhimurium 0.39 1.56 0.39 0.78 0.39 12.5 12.5 0.39 0.39
P. vulgaris 1.56 6.25–3.13 3.13 3.13 3.13 >12.5 >12.5 3.125 6.25–3.13
P. aeruginosa 3.13 6.25 3.13 6.25 3.13 12.5 12.5 6.25 3.13
E. coli O157 3.13 12.5 6.25 6.25 3.13 >12.5 6.25 6.25 3.13
L. monocytogenes 0.39 6.25 0.78 1.56 0.39 >12.5 >12.5 0.78 0.78
Fungi
T. beigelii 1.56 3.13 1.56 1.56 1.56 12.5 12.5 3.13 1.56
C. albicans 12.5 >25 25 25 12.5 >25 >25 >25 12.5
S. cerevisiae 12.5 >25 25 25 25 >25 >25 25 25
A. flavus 25 50 50 50 25 >50 >50 50 50
A. fumigatus 12.5 >50 50 50 25 >50 >50 50-25 50-25
F. moniliforme 12.5 25 12.5 25 12.5 >50 >50 12.5 12.5
B. cinerea 1.56 12.5 6.25 6.25 3.13 >50 >50 12.5 6.25

* melittin

† HP (2-20).