Table 2. Characteristics of mitochondrial proteins labelled by bt-15d-PGJ₂.

The mitochondrial proteins listed in Table 1 are summarized together with their location in the cell, if known. The carboxylases (*) are endogenously biotinylated and may not therefore have formed a stable adduct with bt-15d-PGJ₂.

Protein	Cellular location	Function/comment	Reference
*Pyruvate carboxylase	Mitochondrial	Biotin containing
*Propionyl-CoA carboxylase, β-polypeptide	Mitochondrial	Biotin containing
*Methylcrotonoyl-CoA carboxylase 2 (β) (predicted)	Mitochondrial	Biotin containing
Glutamate dehydrogenase	Matrix	Glutamate metabolism	[43]
3-Hydroxybutyrate dehydrogenase	Mitochondrial membrane	Metabolism of ketone bodies	[44]
Aldehyde dehydrogenase	Matrix	Detoxification of aldehydes	[45]
3-Hydroxyacyl-CoA dehydrogenase type II	Mitochondrial	Fatty acid β-oxidation	[46]
Hydroxyacyl-CoA dehydrogenase	Mitochondrial	Fatty acid β-oxidation	[47]
Acetyl-CoA acyltransferase 2	Mitochondrial	Fatty acid β-oxidation	[48]
3-Hydroxy-3-methylglutaryl-CoA synthase 2	Mitochondrial	Synthesis of mevalonate	[49]
Carbamoyl-phosphate synthetase 1	Matrix	Urea cycle	[50]
Catalase	Peroxisomes/matrix	Removal of hydrogen peroxide	[36]
ANT	Inner membrane	ATP/ADP translocation	[17]
ATP synthase subunits: α, β, FO complex subunit d, subunit o	Inner membrane	ATP synthesis	[51]
Ubiquinol-cytochrome c reductase core protein II	Inner membrane	Electron transfer	[31]
Mortalin (MTHSP70)	Mitochondrial, endoplasmic reticulum, cytosol	Protein folding	[52]
Heat-shock protein 1 (chaperonin)	Mitochondria	Protein folding	[53]