Table 1.
Comparisons of relative differences (ratios of normalized hybridizations) in hypothalamic gene expression in photosensitive (LD, SD) and photorefractory (SDR) hamsters as indicated by cDNA microarray analyses (see Methods)
| Relative difference, fold Δ | Gene name | Function |
|---|---|---|
| LD vs. SD | ||
| +2.5 | Protein phosphatase 1A | Phosphorylation, intracellular signal transduction |
| −2.2 | GnRH receptor | Neuroendocrine feedback, sex behavior |
| −1.1 | P3/GdX | X-linked gene, housekeeping |
| LD vs. SDR | ||
| +2.5 | Transthyretin | Thyroid hormone transport |
| +2.4 | Protein phosphatase 1A | Phosphorylation, intracellular signal transduction |
| 1.0 | P3/GdX | X-linked gene, housekeeping |
| SD vs. SDR | ||
| +2.7 | GnRH receptor | Neuroendocrine feedback, sex behavior |
| +2.5 | Transthyretin | Thyroid hormone transport |
| +2.2 | Solute carrier, family 1, member 2 | Energy transfer |
| −2.3 | Protein phosphatase 1A | Phosphorylation, intracellular signal transduction |
| −1.1 | P3/GdX | X-linked gene, housekeeping |
In each pairwise competitive hybridization experiment, positive values indicate relative up-regulation of gene expression in the treatment group listed first, and negative values indicate relative down-regulation of gene expression in the treatment group listed first. For each hybridization experiment, value is also listed for the transcriptionally active “housekeeping” (23) genes P3 and GdX (value reflects mean hybridization ratio for three separate P3/GdX probes included on the microarray; GenBank accession nos. AA655428, AI550986, and AA061673).