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. 1987 Jul;24(1):57–61. doi: 10.1111/j.1365-2125.1987.tb03136.x

Enprofylline disposition in the presence and absence of amoxycillin or erythromycin.

D S Sitar, F Y Aoki, D J Hoban, K G Hidinger, P R Montgomery, P A Mitenko
PMCID: PMC1386280  PMID: 3620286

Abstract

1 The kinetic disposition of a novel xanthine bronchodilator, enprofylline, was determined in young healthy male volunteers in the presence and absence of amoxycillin or erythromycin. These data were compared to those derived from a similar study of theophylline disposition in the presence and absence of erythromycin. 2 Erythromycin inhibited theophylline disposition only in those subjects in whom the control kinetic study was done after antibiotic ingestion, but the effect was modest. Erythromycin had no effect on enprofylline disposition. 3 Amoxycillin reduced the renal clearance of enprofylline, but the change was not statistically significant.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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