Table 1.
Quantification of change in the microtubule array following cytochalasin D and ML-7 treatment
MT length (μm) | MT number | (n) | |
---|---|---|---|
Control | 5.75 ± 0.08 | 22.14 ± 0.14 | 278 |
Cytochalasin D | 11.67 ± 0.17 | 30.19 ± 0.28 | 171 |
ML-7 | 11.99 ± 0.16 | 30.62 ± 0.4 | 237 |
The MT array in PMNs was quantified by manually tracing the paths of anti-α-tubulin labeled filaments from confocal images. Data represent average number and length (μm) ± SEM of individual microtubules from 18 control, 11 cytochalasin D-treated (Fig. 4), and 11 ML-7-treated cells (Fig. 5) from two independent experiments. (n), the number of individual microtubules analyzed for each condition.