Table 2.

Treatment comparisons (budesonide/formoterol vs formoterol) for all FEV₁ outcome variables

	Mean % change from baselinea
Variable	Formoterol (n = 57)	Budesonide/formoterol (n = 58)	Budesonide/formoterol vs formoterol: mean ratio, % (95% confidence limits)	p value
Eav	16.5	17.4	100.8 (96.1, 105.7)	0.74
Emax	26.3	27.2	100.7 (95.1, 106.7)	0.80
E3	13.3	14.1	100.7 (96.5, 105.1)	0.75
E15	15.8	16.4	100.5 (95.9, 105.3)	0.82
E60	17.2	18.6	101.2 (95.8, 106.9)	0.67
E90	18.2	19.7	101.3 (95.5, 107.3)	0.67
E180	16.5	16.5	100.0 (93.7, 106.7)	1.0

^aBased on adjusted ratios from an analysis of variance model.

E_av is the average FEV₁ (area under the curve) from the first intake of study drug (-5 minutes) to the +90-minute measurement (primary outcome variable). E_max is the change in FEV₁ from pre-administration to the maximal value after administration. E₃, E₁₅, E₆₀, E₉₀ and E₁₈₀ are the changes in FEV₁ from pre-administration to 3, 15, 60, 90 and 180 minutes after the last administration of the study drug, respectively.

FEV₁ = forced expiratory volume in 1 second.