Figure 6.

(a) Active site of (+)-bornyl diphosphate synthase from Salvia officinalis complexed with Mg²⁺₃ and product bornyl diphosphate (yellow hydrocarbon moiety). Metal ions are represented by gray spheres. Hydrogen bonds and metal coordination interactions are shown as gray and black dotted lines, respectively. (b) Active site of wild-type trichodiene synthase complexed with Mg²⁺₃ and co-product PP_i. Metal ions are represented by gray spheres. Hydrogen bonds and metal coordination interactions are shown as gray and black dotted lines, respectively. The view corresponds to that in (a), from within the active site.