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No significant docking is observed during lipid mixing reactions mediated by the neuronal SNAREs. The figure shows a cryo-EM image of a mixture of donor and acceptor vesicles prepared under the same conditions to those used for the lipid mixing assays shown in Fig. 1 A. The sample was fast-frozen a few minutes after mixing donor and acceptor proteoliposomes. The scale bar corresponds to 100 nm.
