Table 1.

Immunogenic peptides derived from HER2/neu protein that are naturally processed and presented

MHC	Peptide	Sequence	Reference
HLA-A*0201	HER2 5–13	ALCRWGLLL	[19]
	HER2 106–114	QLFEDNYAL	[20]
	HER2 369–377	KIFGSLAFL	[7,19,20,21]
	HER2 435–443	ILHNGAYSL	[19,22]
	HER2 654–662	IISAVVGIL	[23]
	HER2 665–673	VVLGVVFGI	[22]
	HER2 689–697	RLLQETELV	[20]
	HER2 773–782	VMAGVGSPYV	[21]
	HER2 789–797	CLTSTVQLV	[7]
	HER2 799–807	QLMPYGCLL	[7]
	HER2 835–842	YLEDVRLV	[7]
	HER2 851–859	VLVKSPNHV	[7]
	HER2 952–961	YMIMVKCWMI	[22]
	HER2 971–979	ELVSEFSRM	[7]
HLA-A*0301†	HER2 754–762	VLRENTSPK	[24]
HLA-A*2402	HER2 8–16	RWGLLLALL	[25]
	HER2 63–71	TYLPTNASL	[26]
	HER2 780–788	PYVSRLLGI	[27]
HLA-DR1, DR4, DR52, DR53	HER2 883–899	KVPIKWMALESILRRRF	[8]

MHC, Major histocompatibility complex. ^†Also binds to three other alleles of the HLA-A3 superfamily: A*1101, A*3101 and A*3301.