TABLE 2.

SBI susceptibilities of S. cerevisiae strains and rox1Δ derivatives^a

Inhibitor	IC50 (μg/ml)
	RZ53-6		YJN433
	ROX1	rox1Δ	ROX1	rox1Δ
Fluconazole	6.2	23	1.1	8.3
Itraconazole	0.30	5.1	0.34	5.2
Miconazole	0.17	0.40	0.09	0.23
Terbinafine	3.0	11	0.06	0.56

^aSusceptibilities were determined by serial dilution in 96-well plates as previously described (10), except that YPD medium at 30°C was employed. IC₅₀s were estimated by extrapolation from the results for the two wells spanning the 50% growth point (control absorbance × 0.5).