Table 2.

Numbers of women randomized, follow-up periods and breast cancers detected (including in situ lesions)

			Cancers
Trial	Total randomized	Median follow up (months)	Total	Tamoxifen/raloxifene	Placebo	OR
RMH [5*]	2 471	70	70	34	36	0.94
NSABP [3*]	13 388	57	368	124	244	0.51
Italian [6*]	5 408	46	41	19 (11)†	22(19)‡	0.91
IBIS*	6 037	30	88	-*	-*	-*
MORE [7*]	7 705	40	54	22/2‡	32	0.35

^*As of 1 December 1999 (ongoing and still blinded). ^†Tamoxifen >1 year. ^‡2:1 ratio of raloxifene:placebo in MORE study.