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Some microRNA families, such as the mir-10 and mir-100 (left), exhibit very similar mature miRNA sequences, while their precursor sequences show little sequence similarity. Right: A table of alignment z-score for both mature and precursor sequences summarizes the four most likely candidates for distance homologies. While the mir-8/mir-429 pair is most likely a true homolog, the other three pairs are unconvincing, see text.
