Table 3.
Predictors of mortality via multiple logistic regression in African children with malaria, by site.
| Characteristic | Blantyre, Malawi(n = 2159) | Kilifi, Kenya(n = 4670) | Kumasi, Ghana(n = 3730) |
|---|---|---|---|
| Weight-for-age Z score (per unit increase) | 0.84 (0.71–1.01) | 0.75 (0.68–0.82) | 0.90 (0.81–0.99) |
| Deep breathing | 3.78 (1.76–8.14) | 1.53 (0.99–2.36) | 2.26 (1.57–3.27) |
| Blantyre coma score ≤2 | 2.29 (1.05–5.03) | 1.93 (1.25–2.99) | 3.15 (2.18–4.56) |
| Unable to sit | 3.64 (1.73–7.63) | 2.65 (1.68–4.17) | 1.83 (1.17–2.85) |
| Hypoglycemiaa | 2.17 (0.77–6.12) | 2.48 (1.57–3.92) | 2.10 (1.34–3.29) |
| Lactate (per mmol/l increase) | 1.05 (0.99–1.12) | … | 1.02 (0.98–1.07) |
| Base excess (per unit decrease) | 1.14 (1.08–1.21) | 1.13 (1.09–1.17) | 1.11 (1.07–1.15) |
| c Statistic | 0.88 | 0.87 | 0.83 |
NOTE. Data are OR (95% CI), unless otherwise indicated. There were a total of 59 deaths in Blantyre, 156 deaths in Kilifi, and 183 deaths in Kumasi. P values were <.05 whenever an OR of 1.0 was excluded from the 95% CI. Also, P = .06 for weight-for-age Z score, P= .14 for hypoglycemia, and P = .14 for lactate concentration in Blantyre; P = 06 for deep breathing in Kilifi; and P = .31 for lactate concentration in Kumasi.
a
Glucose level, ≤2.2 mmol/L.