Figure 3.

Nucleotide sequences and cleavage activities of delta ribozyme variants obtained by in vitro selection. Regions that were randomized in the initial ribozyme library are marked in bold. All nucleotides that differ from those found at corresponding positions of the wild-type ribozyme sequence (WT) are denoted by red fonts. Cleavage extents (in percentages) were determined for trans-acting forms of ribozymes after 10 min in the presence of 10 mM Mg²⁺.