TABLE 1.
Variable | Mean (range) ± SD |
---|---|
Age (years) | 39 (25–54) ± 6.6 |
BMI (kg/m2) | 31 (21–48) ± 4.9 |
Waist-to-hip circumference ratio | 0.86 (0.72–1.32) ± 0.07 |
OGTT fasting plasma glucose (mg/dl)* | 99 (81–124) ± 9.7 |
OGTT 2-h plasma glucose (mg/dl)* | 151 (97–199) ± 27.6 |
OGTT glucose area (mg · dl−1 · min−1 · 10−3)* | 18.3 (12.0–24.7) ± 2.8 |
OGTT fasting plasma insulin (μU/ml)* | 17.4 (5–64) ± 10.4 |
OGTT insulin area (μU · ml−1 · min−1)* | 11,058 (3,165–30,120) ± 6,662 |
A1C (% of hemoglobin) | 5.7 (4.4–6.6) ± 0.5 |
Si (min · μU−1 · ml−1 · 10−4)† | 2.33 (0.37–10.90) ± 1.65 |
AIRg (μU · ml−1 · min−1)‡ | 408 (−3 to 1,342) ± 292 |
DI§ | 834 (−2 to 2,418) ± 583 |
IVGTT insulin area (μU · ml−1 · min−1)¶ | 9,654 (2,503–36,172) ± 5,743 |
Data are means (range) ± SD.
75-g OGTT; areas are total calculated by trapezoid rule.
Minimal model analysis of IVGTT results.
Incremental insulin area during the first 10 min after glucose injection.
Si × AIRg, a measure of β-cell compensation for insulin resistance.
Total area from 0 to 240 min. To convert values for glucose to mmol/l, multiply by 0.05551. To convert values for insulin to pmol/l, multiply by 6.0.