TABLE 2.
New extragenic suppressors of the lin-12(d) 0 AC-Egl defect
| Alleles of new sel genes | Relevant mapping and sequencing data | Penetrancea (% egg laying competent/total) |
|---|---|---|
| LG I | ||
| ar526 | Complements sup-17(n1258) | 10 (n = 68) |
| LG III | ||
| ar562 | Maps to the right of unc-36; no sequence changes in the lin-12 or bre-3 coding regions. | 37 (n = 49) |
| LG IV | ||
| ar560 | 4 (n = 193) | |
| ar584 | 17 (n = 51) | |
| ar522, ar570 | Single complementation group | 15 (n = 40), 17 (n = 93) |
| LG V | ||
| ar578 | No sequence changes in lag-2 and skp-1 coding regions; ar578 maps to the left of sel-6. | 5 (n = 40) |
a
Penetrance of the suppression of the egg-laying defect (after at least two backcrosses) was determined at 20° in animals homozygous for the indicated mutation and unc-36(e251) lin-12(n302) from Table 1.