Figure 3. PFC (Cg1–PLC) activity during a cocaine self-administration session in which the cocaine infusion is omitted on a random 50% of trials.

Data are presented as in Figure 1. Left: Trials with cocaine infusion (infusion pump on from 0–4 s). Note the brief activation of unit activity almost immediately after cue onset. Right: Trials without cocaine infusion. Note the similarity of the left and right PETHs throughout the 20-s period after cue onset.