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. 2001 Nov 23;2(12):reviews3014.1–reviews3014.7. doi: 10.1186/gb-2001-2-12-reviews3014

Table 2.

Mouse and human granzymes grouped according to their chromosomal localization

Chromosomal localization Species Granzyme(s)
The 'tryptase' locus
 5q11-q12 Human A and tryptase-2
 13D Mouse A
The 'chymase' locus
 14q11-q12 Human B and H
 14D Mouse B,C,D*,E,F and G*
The 'Met-ase' locus
 19p13.3 Human M
 10q21.2 Mouse M

*Granzymes D and G have not been definitively mapped, but are highly homologous to granzymes E and B, respectively.