Table 3.

Comparison of various combinations of three diagnostic methods for preoperative prediction of histologically confirmed invasive cancer (n = 185) or benign disease (n = 254)

Diagnostic methods	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)	Accuracy (%)
Mammography + MR mammography	98.9*	90.5	88.4	99.1*	94.1
Sonography + MR mammography	98.9*	93.3	91.5	99.2*	95.7
Mammography + sonography	94.6	92.1	89.7	95.9	93.2
All three methods combined	99.4†	95.3	93.9	99.6†	97.0†‡

^*P < 0.05, versus mammography and sonography; ^†P < 0.005, versus mammography and sonography; ^‡P < 0.05, versus MR mammography and mammography. NPV, negative predictive value; PPV, positive predictive value.